Electrolyte-derived clinical indices in traumatic brain injury: A narrative review

doi:10.5662/wjm.v16.i2.111570

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World Journal of Methodology

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2222-0682

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World J Methodol. Jun 20, 2026; 16(2): 111570
Published online Jun 20, 2026. doi: 10.5662/wjm.v16.i2.111570

Table 3 Electrolyte correction formulas in traumatic brain injury

Correction	Formula	Use case	Importance
Corrected sodium (mg/dL glucose)[50,51]	Na⁺ + 0.016 × (glucose − 100)	Hyperglycemia	Prevents misdiagnosis of hyponatremia
Corrected sodium (mmol/L glucose)[50,51]	Na⁺ + 0.024 × (glucose − 5.6)	Hyperglycemia (SI units)	Same as above
Corrected calcium (g/dL albumin)[51]	Ca + 0.8 × (4 − albumin)	Hypoalbuminemia	Prevents under-treatment of hypocalcemia
Corrected calcium (g/L albumin)[51]	Ca + 0.02 × (40 − albumin)	Hypoalbuminemia (SI units)	Same as above

SI: Standard international.

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Citation: Mekkodathil A, El-Menyar A, Rizoli S, Al-Thani H. Electrolyte-derived clinical indices in traumatic brain injury: A narrative review. World J Methodol 2026; 16(2): 111570
URL: https://www.wjgnet.com/2222-0682/full/v16/i2/111570.htm
DOI: https://dx.doi.org/10.5662/wjm.v16.i2.111570

Mekkodathil A, El-Menyar A, Rizoli S, Al-Thani H. Electrolyte-derived clinical indices in traumatic brain injury: A narrative review. World J Methodol 2026; 16(2): 111570 [PMID: 42058810 DOI: 10.5662/wjm.v16.i2.111570]

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