Clinical insights into levothyroxine overdose: A systematic review

doi:10.5662/wjm.v16.i2.111025

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 2

This Article

(47)

(41)

(0)

(52)

(3643)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Methodology

ISSN

2222-0682

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Systematic Reviews

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Methodol. Jun 20, 2026; 16(2): 111025
Published online Jun 20, 2026. doi: 10.5662/wjm.v16.i2.111025

Table 2 Symptoms and complications in 95 patients with levothyroxine toxicity from published case reports and series¹

Variable	Frequency (%)
Tachycardia	37 (38.95)
Confusion	22 (23.16)
Fever	18 (18.95)
Tremors	13 (13.68)
Palpitations	12 (12.63)
Diarrhea	10 (10.53)
Vomiting	8 (8.42)
Heat intolerance	7 (7.37)
Sweating	6 (6.32)
Shortness of breath	6 (6.32)
Atrial fibrillation	5 (5.26)
Dizziness	4 (18.18)
Weight loss	3 (3.16)
Periodic paralysis	3 (3.16)
Bradycardia	2 (2.11)
Heart failure	2 (2.11)
Ophthalmopathy	1 (1.05)
In-hospital mortality	1 (1.05)

¹Some patients experienced multiple symptoms or complications; therefore, the total percentage exceeds 100%.

Full Size Table

Citation: Ata F, Khan HA, Kashif A, Khan AA, Fawad R, Younas HW, Ahmed B, Javed H. Clinical insights into levothyroxine overdose: A systematic review. World J Methodol 2026; 16(2): 111025
URL: https://www.wjgnet.com/2222-0682/full/v16/i2/111025.htm
DOI: https://dx.doi.org/10.5662/wjm.v16.i2.111025

Ata F, Khan HA, Kashif A, Khan AA, Fawad R, Younas HW, Ahmed B, Javed H. Clinical insights into levothyroxine overdose: A systematic review. World J Methodol 2026; 16(2): 111025 [PMID: 42058803 DOI: 10.5662/wjm.v16.i2.111025]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.