Copyright: ©Author(s) 2026.
World J Methodol. Jun 20, 2026; 16(2): 111025
Published online Jun 20, 2026. doi: 10.5662/wjm.v16.i2.111025
Published online Jun 20, 2026. doi: 10.5662/wjm.v16.i2.111025
Table 1 Baseline demographics and clinical characteristics of 95 patients with levothyroxine toxicity from published case reports, series, and more extensive studies with individualizable data, n (%)/median (25th-75th percentiles)
| Characteristic | n | Results |
| Age (years) | 87 | 20 (3.5-42) |
| Gender | 62 | |
| Female | 41 (66.13) | |
| Male | 21 (33.87) | |
| Comorbidities | 95 | |
| Psychiatric disorder | 9 (9.47) | |
| Diabetes mellitus | 4 (4.21) | |
| Chronic kidney disease | 3 (3.16) | |
| Heart failure | 2 (2.11) | |
| COPD/asthma | 1 (1.05) | |
| Highest heart rate (beats/minute) | 47 | 110 (89-128) |
| Highest systolic blood pressure (mm Hg) | 41 | 115 (100-130) |
| Highest diastolic blood pressure (mm Hg) | 40 | 70 (61.5-80) |
| Lowest potassium level (mmol/L) | 7 | 3.6 (2.4-4.3) |
| Highest temperature (°C) | 29 | 36.7 (36.4-37) |
| Highest creatinine (mmol/L) | 16 | 0.039 (0.026-0.057) |
| Cumulative amount of levothyroxine (μg) | 54 | 4250 (1250-10000) |
| Time from overdose to presentation (hours) | 48 | 4.5 (1.5-24) |
- Citation: Ata F, Khan HA, Kashif A, Khan AA, Fawad R, Younas HW, Ahmed B, Javed H. Clinical insights into levothyroxine overdose: A systematic review. World J Methodol 2026; 16(2): 111025
- URL: https://www.wjgnet.com/2222-0682/full/v16/i2/111025.htm
- DOI: https://dx.doi.org/10.5662/wjm.v16.i2.111025