Effects of rosuvastatin treatment and other statins on burn wound healing

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World Journal of Methodology

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2222-0682

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World J Methodol. Mar 20, 2026; 16(1): 112686
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.112686

Table 3 Efficacy of rosuvastatin on wound healing in recent experimental studies

Ref.	Subjects	Intervention	Groups	Outcome
Santana et al[1], 2025	8 male New Zealand rabbits	Dermal wounds, RSV gel, autologous PRP 32 biopsies	The autologous PRP, RSV, PRP + RSV, control	PRP + RSV has higher collagen I than control
Marneri et al[2], 2024	36 male Wistar rats	Burn trauma, RSV topical	RSV, control (placebo)	RSV higher fibroblast proliferation, angiogenesis, re-epithelization, lower tumor necrosis factor-α, procalcitonin
Zaki et al[5], 2022	30 male Wistar rats	Skin wounds RSV transe-hosomal	Silver sulp-hadiazine RSV-loaded gel control	Nanovesicles enhanced wound healing
Salem et al[6], 2022	30 female Wistar rats	Skin wounds	RSV nano-cubics 16 mg plus RSV 1.4 mg/g hydrogel alone RSV or AgNPs or gentamicin control	Biogel RSV plus AgNPs enhanced wound healing

AgNPs: Silver nanoparticles; PRP: Platelet-rich plasma; RSV: Rosuvastatin.

Citation: Marneri AG, Pavlidis ET, Stavrati KE, Mouratidou C, Kotoulas SC, Ballas KD, Pavlidis TE. Effects of rosuvastatin treatment and other statins on burn wound healing. World J Methodol 2026; 16(1): 112686
URL: https://www.wjgnet.com/2222-0682/full/v16/i1/112686.htm
DOI: https://dx.doi.org/10.5662/wjm.v16.i1.112686

Marneri AG, Pavlidis ET, Stavrati KE, Mouratidou C, Kotoulas SC, Ballas KD, Pavlidis TE. Effects of rosuvastatin treatment and other statins on burn wound healing. World J Methodol 2026; 16(1): 112686 [PMID: 41809179 DOI: 10.5662/wjm.v16.i1.112686]

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