Methodological insights into fecal microbiota transplantation: Dissecting key approaches for success

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Mar 20, 2026; 16(1): 108875
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.108875

Table 7 Regulatory variations in fecal microbiota transplantation

Country	FMT classification
United States	Restricted use in CDI in line with FDA enforcement discretion policy[78]; investigational new drug approval used in context of clinical trials for other diseases
Belgium, Netherlands, Italy	Regulated as a tissue transplant, under European Union Tissue and Cells Directive
Australia	Regulated as a biological drug
United Kingdom, Germany, France, Ireland, Switzerland	Regulated as a medicinal drug -flexible use allowed

FMT: Fecal microbiota transplantation; CDI: Clostridioides difficile infection.

Citation: Mundhra SK, Kochhar R. Methodological insights into fecal microbiota transplantation: Dissecting key approaches for success. World J Methodol 2026; 16(1): 108875
URL: https://www.wjgnet.com/2222-0682/full/v16/i1/108875.htm
DOI: https://dx.doi.org/10.5662/wjm.v16.i1.108875

Mundhra SK, Kochhar R. Methodological insights into fecal microbiota transplantation: Dissecting key approaches for success. World J Methodol 2026; 16(1): 108875 [PMID: 41809178 DOI: 10.5662/wjm.v16.i1.108875]

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