Methodological insights into fecal microbiota transplantation: Dissecting key approaches for success

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Mar 20, 2026; 16(1): 108875
Published online Mar 20, 2026. doi: 10.5662/wjm.v16.i1.108875

Table 4 Comparative analysis of different stool processing methods

Method	Pros	Cons	Recommended setting
Rough filtration	Simple, low cost	Low microbial purity, higher adverse events	Suitable for basic setups
Filtration plus centrifugation	Improved bacterial concentration	Moderate technical demands	Used in standard protocols
Microfiltration plus centrifugation	High microbial purity, fewer toxic reactions, delivers a precise dose of the enriched microbiota instead of using the weight of stool	Expensive, automated system e.g., GenFMTer needed	Ideal for advanced centers

Citation: Mundhra SK, Kochhar R. Methodological insights into fecal microbiota transplantation: Dissecting key approaches for success. World J Methodol 2026; 16(1): 108875
URL: https://www.wjgnet.com/2222-0682/full/v16/i1/108875.htm
DOI: https://dx.doi.org/10.5662/wjm.v16.i1.108875

Mundhra SK, Kochhar R. Methodological insights into fecal microbiota transplantation: Dissecting key approaches for success. World J Methodol 2026; 16(1): 108875 [PMID: 41809178 DOI: 10.5662/wjm.v16.i1.108875]

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