Association of neutrophil-lymphocyte ratio with all-cause and cardiovascular mortality in peritoneal dialysis patients: A systematic review and meta-analysis

Table 4 Subgroup meta-analysis for all-cause mortality

Variables	Number of studies	Number of patients	Adjusted hazard ratio (95%CI)	P value	I2
Study design
Prospective	3	656	1.06 (0.58-1.97)	0.84	83.6
Retrospective	3	2129	1.10 (1.00-1.21)	0.047	77
Sample size
< 350	4	692	1.27 (0.74-2.15)	0.38	84.8
≥ 350	3	3658	1.11 (1.03-1.19)	0.004	61.3
Males
< 59	2	1640	0.90 (0.37-2.18)	0.81	90.1
≥ 59	3	2143	1.08 (1.02-1.14)	0.01	45.8
Diabetes
< 32	3	1780	1.18 (0.55-2.56)	0.67	85.4
≥ 32	2	2003	1.07 (1.04-1.10)	< 0.0001	< 0.0001
Neutrophil-to-lymphocyte ratio (109/L)
2.87-3.2	2	1918	1.47 (0.64-3.41)	0.37	72.2
3.3-3.89	3	1865	0.99 (0.69-1.42)	0.96	80.4
Serum albumin (g/dL)
< 3.5	3	2069	1.42 (1.01-1.99)	0.04	76.4
≥ 3.5	4	2281	1.05 (0.95-1.17)	0.32	73.6