Uncovering the role of microbiota and fecal microbiota transplantation in Crohn’s disease: Current advances and future hurdles

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Dec 20, 2025 (publication date) through Aug 15, 2025

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World Journal of Methodology

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2222-0682

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Methodol. Dec 20, 2025; 15(4): 106148
Published online Dec 20, 2025. doi: 10.5662/wjm.v15.i4.106148

Table 3 Role of probiotics in the maintenance of remission in Crohn’s disease

Ref.	Type of study	Number (n)	Findings
Garcia et al[23]	RCT	Treatment group (n = 14). Control group (n = 17)	Improvement in clinical activity
Bourreille et al[24]	DB-RCT	Treatment group (n = 80). Control group (n = 79)	No benefits of probiotics
Bjarnason et al[25]	RCT	Treatment group (n = 33). Control group (n = 29)	No benefits of probiotics
Marteau et al[26]	DB RCT	Treatment group (n = 48). Control group (n = 50)	No benefits of probiotics

DB: Double blind; RCT: Randomized controlled trial.

Citation: Singh JP, Aleissa M, Chitragari G, Drelichman ER, Mittal VK, Bhullar JS. Uncovering the role of microbiota and fecal microbiota transplantation in Crohn’s disease: Current advances and future hurdles. World J Methodol 2025; 15(4): 106148
URL: https://www.wjgnet.com/2222-0682/full/v15/i4/106148.htm
DOI: https://dx.doi.org/10.5662/wjm.v15.i4.106148