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World J Methodol. Dec 20, 2025; 15(4): 106148
Published online Dec 20, 2025. doi: 10.5662/wjm.v15.i4.106148
Table 2 Role of probiotics in inducing remission in Crohn’s disease
Ref.
Type of study
Number (n)
Findings
Gupta et al[19]Open label 4 CD patients. No control group Improvement in clinical activity
Schultz et al[20]DB RCTTreatment group (n = 5). Control group (n = 6)No benefits of probiotics
Fujimori et al[21]Open label10 CD patients. No control groupDecrease in CDAI
Steed et al[22]DB RCTTreatment group (n = 13). Control group (n = 11)Decrease in CDAI