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Copyright ©The Author(s) 2025.
World J Methodol. Dec 20, 2025; 15(4): 104497
Published online Dec 20, 2025. doi: 10.5662/wjm.v15.i4.104497
Table 2 The advantages and disadvantages of different chemical agents
Chemicals
Advantages
Disadvantages
EpinephrineGood tissue displacementSystemic reactions
Minimal tissue lossEpinephrine syndrome
Good hemostasisRisk of inflammation of the gingival cuff
Rebound hyperemia
Risk of tissue necrosis
AlumMinimal tissue lossLess hemostasis and tissue displacement
Extended working timeOffensive taste
Risk of necrosis if in high concentration
Aluminum chlorideMinimal tissue lossLocal tissue destruction
Good hemostasisLess vasoconstriction than epinephrine
No systemic effectsRisk of sulcus contamination
Least irritating of all chemicalsModifies surface detail reproduction
HemostasisInhibits set of polyvinyl siloxane and polyether impressions
Little sulcus collapse after cord removal
Ferric sulfateCompatible with aluminum chlorideNon compatible with epinephrine
Tissue discoloration
Good displacement Acidic taste
Risk of sulcus contamination Inhibits set of polyvinyl siloxane and polyether impressions
Tannic acidGood tissue response Less displacement
Minimal hemostasis