©The Author(s) 2025.
World J Methodol. Dec 20, 2025; 15(4): 102758
Published online Dec 20, 2025. doi: 10.5662/wjm.v15.i4.102758
Published online Dec 20, 2025. doi: 10.5662/wjm.v15.i4.102758
Table 1 Demographic characteristics of the population of depressed and non-depressed elderly adults that underwent total knee arthroplasty, n (%)
| Characteristic | With depression (n = 22) | Without depression (n = 78) | P value |
| Female sex | 14 (64) | 51 (65) | 0.9 |
| Age (years) | 77.6 ± 6 | 80.6 ± 6.3 | 0.05 |
| Body mass index | 31.4 ± 6.3 | 30.8 ± 4.7 | 0.6 |
| Charlson index (IQR) | 1 (0-1) | 1 (0-2) | 0.1 |
| Diabetes | 2 (9) | 14 (18) | 0.5 |
| Hypertension | 16 (73) | 70 (90) | 0.04 |
| Hypothyroidism | 2 (9) | 23 (29) | 0.06 |
| Number of medications used | 6.6 ± 3.5 | 7.6 ± 3.2 | 0.2 |
| Older Americans Resources and Services Social Resource Scale (IQR) | 1.5 (1-2) | 1 (1-2) | 0.3 |
| Use of antidepressant medication | 7 (32) | 20 (26) | 0.6 |
| Use of Potentially Inappropriate Medication (Beers Criteria) | 18 (82) | 50 (64) | 0.1 |
| ADL (IQR) | 4.5 (4-5) | 5 (4-6) | 0.2 |
| Decreased ADL (< 6) | 18 (82) | 49 (63) | 0.09 |
| IADL (IQR) | 6 (3-7) | 6 (4-8) | 0.3 |
| Decreased IADL (< 6) | 10 (45) | 27 (35) | 0.4 |
| Clock-Drawing test (IQR) | 5 (3-6) | 6 (5-7) | 0.06 |
| Cognitive Impairment (Mini Mental score < 24 or Mini-Cog < 3) | 6 (27) | 27 (35) | 0.5 |
| Impaired gait speed test (more than 7 seconds per 4.5 meters) | 15 (71) | 47 (62) | 0.5 |
| Impaired chair stand test (greater than 15 seconds) | 18 (95) | 53 (79) | 0.2 |
| Risk factors for Confusional Syndrome | 8 ± 2 | 6.5 ± 2.2 | 0.006 |
| Edmonton Frail Scale | 8 ± 2.5 | 5.8 ± 2.6 | 0.0006 |
| Frailty according to Edmonton (≥ 7) | 15 (68) | 33 (42) | 0.05 |
| Fried Frailty Index | 3.3 ± 1.2 | 2.5 ± 1.3 | 0.01 |
| Frailty according to Fried (≥ 3) | 17 (77) | 42 (54) | 0.05 |
| Number of falls in the past year | 12 (55) | 28 (36) | 0.1 |
| Hand Grip (kg) (IQR) | 18.5 (12-27) | 19 (14-28) | 0.5 |
| Preoperative Knee KSS | 27.4 ± 20.7 | 33.6 ± 16.5 | 0.2 |
| Preoperative Functional KSS | 31.8 ± 19.6 | 33.2 ± 21.2 | 0.8 |
- Citation: Nicolino TI, Smietniansky M, Boietti B, Garcia-Mansilla I, Carbo L, Martinez CB. Impact of depression on functional status in elderly patients undergoing total knee arthroplasty. World J Methodol 2025; 15(4): 102758
- URL: https://www.wjgnet.com/2222-0682/full/v15/i4/102758.htm
- DOI: https://dx.doi.org/10.5662/wjm.v15.i4.102758