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Retrospective Cohort Study
©The Author(s) 2025.
World J Methodol. Dec 20, 2025; 15(4): 102758
Published online Dec 20, 2025. doi: 10.5662/wjm.v15.i4.102758
Table 1 Demographic characteristics of the population of depressed and non-depressed elderly adults that underwent total knee arthroplasty, n (%)
Characteristic
With depression (n = 22)
Without depression (n = 78)
P value
Female sex14 (64)51 (65)0.9
Age (years)77.6 ± 680.6 ± 6.30.05
Body mass index31.4 ± 6.330.8 ± 4.70.6
Charlson index (IQR)1 (0-1)1 (0-2)0.1
Diabetes2 (9)14 (18)0.5
Hypertension16 (73)70 (90)0.04
Hypothyroidism2 (9)23 (29)0.06
Number of medications used6.6 ± 3.57.6 ± 3.20.2
Older Americans Resources and Services Social Resource Scale (IQR)1.5 (1-2)1 (1-2)0.3
Use of antidepressant medication7 (32)20 (26)0.6
Use of Potentially Inappropriate Medication (Beers Criteria)18 (82)50 (64)0.1
ADL (IQR)4.5 (4-5)5 (4-6)0.2
Decreased ADL (< 6)18 (82)49 (63)0.09
IADL (IQR)6 (3-7)6 (4-8)0.3
Decreased IADL (< 6)10 (45)27 (35)0.4
Clock-Drawing test (IQR)5 (3-6)6 (5-7)0.06
Cognitive Impairment (Mini Mental score < 24 or Mini-Cog < 3)6 (27)27 (35)0.5
Impaired gait speed test (more than 7 seconds per 4.5 meters)15 (71)47 (62)0.5
Impaired chair stand test (greater than 15 seconds)18 (95)53 (79)0.2
Risk factors for Confusional Syndrome8 ± 26.5 ± 2.20.006
Edmonton Frail Scale8 ± 2.55.8 ± 2.60.0006
Frailty according to Edmonton (≥ 7)15 (68)33 (42)0.05
Fried Frailty Index3.3 ± 1.22.5 ± 1.30.01
Frailty according to Fried (≥ 3)17 (77)42 (54)0.05
Number of falls in the past year12 (55)28 (36)0.1
Hand Grip (kg) (IQR)18.5 (12-27)19 (14-28)0.5
Preoperative Knee KSS27.4 ± 20.733.6 ± 16.50.2
Preoperative Functional KSS31.8 ± 19.633.2 ± 21.20.8


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