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©The Author(s) 2025.
World J Methodol. Dec 20, 2025; 15(4): 102408
Published online Dec 20, 2025. doi: 10.5662/wjm.v15.i4.102408
Published online Dec 20, 2025. doi: 10.5662/wjm.v15.i4.102408
Table 7 Comparison between magnetic resonance imaging and computed tomography in gastrointestinal myopathies
Feature | MRI | Computed tomography |
Tissue contrast | Superior soft tissue contrast; excellent for detecting muscle atrophy, fibrosis, and inflammation | Moderate contrast; better for bony structures and acute bleeding |
Radiation exposure | No ionizing radiation—safer for children and repeated follow-ups | Uses ionizing radiation, which may be concerning for pediatric patients and those needing serial imaging |
Visualization of smooth muscle | More detailed assessment of intestinal wall abnormalities, fibrosis, and motility issues | Less sensitive in detecting smooth muscle pathology |
Gastric and intestinal motility | MRI can provide cine imaging for real-time assessment of gastric emptying and intestinal movement | Lacks dynamic imaging capability for motility disorders |
Bowel obstruction and pseudo-obstruction | Can differentiate between true obstruction vs pseudo-obstruction based on bowel wall motion | Effective for detecting acute bowel obstructions but lacks functional assessment |
Detection of liver and pancreatic involvement | Better visualization of hepatic and pancreatic steatosis, common in metabolic myopathies | Good for detecting structural abnormalities, such as tumors or calcifications |
Practical limitations | Longer scan time, requires patient cooperation, contraindicated in patients with metal implants | Quick scan time, widely available, useful for emergency settings |
- Citation: Al-Beltagi M, Saeed N, Bediwy A, Elbeltagi R. Navigating gastrointestinal challenges in genetic myopathies: Diagnostic insights and future directions. World J Methodol 2025; 15(4): 102408
- URL: https://www.wjgnet.com/2222-0682/full/v15/i4/102408.htm
- DOI: https://dx.doi.org/10.5662/wjm.v15.i4.102408