Non-enzymatic methods for isolation of stromal vascular fraction and adipose-derived stem cells: A systematic review

Table 2 Risk of bias in the included studies based on office of health assessment and translation criteria

Ref.	Did the selection of study participants appropriate?	Did the study account for confounding and modifying variables?	Were the outcome data complete without attrition bias?	Can we be confident in exposure characterization?	Can we be confident in outcome assessment?	Were all measured outcomes reported?
Raposio et al[31]	++	+	++	++	++	++
Chaput et al[37]	++	++	+	+	++	+
Cohen et al[32]	++	+	+	- (NR)	+	+
Copcu et al[38]	++	++	++	+	+	++
Tonnard et al[2]	++	+	+	+	+	+
Sesé et al[33]	++	+	+	+	+	+
Rose et al[39]	++	+	++	++	++	++
Bianchi et al[34]	++	++	++	++	++	++
van Dongen et al[22]	++	+	+	- (NR)	+	+
Amirkhani et al[40]	++	++	++	++	++	++
Victor[41]	++	++	++	++	++	++
Bright et al[35]	++	-	+	+	+	+
Domenis et al[42]	++	++	+	- (NR)	+	+
Gentile et al[36]	++	+	+	+	+	+
Condé-Green et al[43]	++	++	++	++	++	++
Markarian et al.[44]	++	++	+	++	++	++
Shah et al[45]	++	++	++	++	++	++
Condé-Green et al[46]	++	++	++	- (NR)	+	+
Baptista et al[47]	++	+	+	++	++	++

NR: Not reported; ++: Reflects a low risk of bias; +: Reflects probably a low risk of bias; -: Reflects probably a high risk of bias.