Compensated liver cirrhosis: Natural course and disease-modifying strategies

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World Journal of Methodology

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2222-0682

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World J Methodol. Sep 20, 2023; 13(4): 179-193
Published online Sep 20, 2023. doi: 10.5662/wjm.v13.i4.179

Table 1 Factors associated with decompensation of compensated liver cirrhosis

Risk factors for non-acute decompensation	Precipitating factors for acute decompensation
Thick fibrous septa and micronodularity on liver biopsy	Bacterial infection
Persistent liver injury by etiological factor	Active alcoholism
High portal pressure	Gastrointestinal haemorrhage
Systemic inflammation & hemodynamic changes	Consumption of hepatotoxic drug/alternative medicine
Metabolic risk factors: DM, obesity, and dyslipidaemia	Superinfection or flare of viral hepatitis
Genetic risk factors: PNPLA3 G/G genotype	Major surgery and general anaesthesia

DM: Diabetes mellitus; PNPLA3: Patatin-like phospholipase domain-containing protein 3.

Citation: Kumar R, Kumar S, Prakash SS. Compensated liver cirrhosis: Natural course and disease-modifying strategies. World J Methodol 2023; 13(4): 179-193
URL: https://www.wjgnet.com/2222-0682/full/v13/i4/179.htm
DOI: https://dx.doi.org/10.5662/wjm.v13.i4.179

Kumar R, Kumar S, Prakash SS. Compensated liver cirrhosis: Natural course and disease-modifying strategies. World J Methodol 2023; 13(4): 179-193 [PMID: 37771878 DOI: 10.5662/wjm.v13.i4.179]

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