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World Journal of Translational Medicine
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2220-6132
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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©The Author(s) 2015.
World J Transl Med. Apr 12, 2015; 4(1): 11-24
Published online Apr 12, 2015. doi: 10.5528/wjtm.v4.i1.11
Table 3 Genes that are epigenetically regulated in cancer
Cancer-associated pathwayGene
Cell cycleRb, p16INK4a, p16INK4b, 14-3-3, cyclin E, p14ARF
Signal transductionErbB2, RASSF1, LKB1/STK11, APC
ApoptosisDAPK gene, Caspase-8 gene
DNA repairMGMT, MHL1, BRCA1, FNACF
Carcinogen metabolismGSTP1 gene
Hormonal responseOestrogen receptor gene, progesterone receptor gene, RAR-b2 gene
SenescenceTERT, TERG
Invasion/metastasisTIMP-3 gene, E cadherin gene, VHL gene
TranscriptionRunx3, Twist, Er α, Er β, PR, RAR, vitamin D receptor
Drug responsivenessGlutatione S-transferase, thymidylate synthase
Adapted by Choi et al[1], 2013.
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