High-potency sucralfate prevents and rapidly reverses chemo-radiation mucositis in a patient with stage 4b head and neck cancer

Table 1 Grade scales for the assessment of oral mucositis

World Health Organization Grade	Grade 1	Grade 2	Grade 3	Grade 4	Grade 5
Function	Painless ulcers, erythema or mild soreness	Painful erythema, edema, or ulcers but can eat solids	Painful erythema, edema, or ulcers and cannot eat solids	Alimentation is not possible; dependence on IV and feeding-tube
Clinical Exam	Erythema of the mucosa	Patchy ulcerations or pseudomembranes	Confluent ulcerations or pseudomembranes; bleeding with minor trauma	Tissue necrosis; significant spontaneous bleeding; life-threatening consequences	Death
Symptoms	Minimal symptoms, normal diet; minimal respiratory symptoms but not interfering with function	Symptomatic but able to eat and swallow modified diet; respiratory symptoms interfering with function but not with activities of daily living	Symptomatic and unable to adequately aliment or hydrate orally; respiratory symptoms interfering with activities of daily living	Symptoms associated with life-threatening consequences	Death