Serum zinc levels, hepatic encephalopathy, and liver disease severity in decompensated chronic liver disease patients in Kano, Nigeria

doi:10.5528/wjtm.124154

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World Journal of Translational Medicine

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2220-6132

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World J Transl Med. Sep 28, 2026; 12(3): 124154
Published online Sep 28, 2026. doi: 10.5528/wjtm.124154

Table 2 Laboratory parameters of subjects according to grades of hepatic encephalopathy

Parameter	All DCLD patients	MHE (n = 16)	Grade I (n = 16)	Grade II (n = 16)	Grade III (n = 16)	Grade IV (n = 16)
INR	1.97 (2.36)	1.28 (0.97)	1.55 (1.34)	2.16 (2.46)	3.23 ± 2.26	3.23 ± 1.68
PT (seconds)	24.80 (29.8)	18.00 (13.00)	18.75 (13.50)	25.50 (28.30)	38.95 ± 24.19	38.08 ± 21.76
AST (U/L)	61.00 (67.00)	33.00 (70.00)	43.00 (57.00)	70.00 (72.00)	59.63 ± 39.53	99.38 ± 56.62
ALT (U/L)	51.50 (52.00)	41.00 (65.00)	57.56 (41.68)	42.50 (37.00)	50.50 (60.00)	70.00 (74.00)
Total bilirubin (µmol/L)	30.00 (44.80)	20.30 (21.50)	14.50 (15.80)	44.61 ± 35.12	59.50 (61.30)	40.00 (39.30)
Albumin (g/L)	28.55 ± 5.96	30.00 (9.00)	31.81 (5.73)	26.44 ± 7.03	25.13 ± 5.21	27.94 ± 4.23

Values are presented as median (interquartile range) or mean ± SD.

MHE: Minimal hepatic encephalopathy; PT: Prothrombin time; INR: International normalized ratio; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; DCLD: Decompensated chronic liver disease.

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Citation: Manzo MGA, Audu N, Musa Y, Muktar AA, Samaila AA, Borodo MM. Serum zinc levels, hepatic encephalopathy, and liver disease severity in decompensated chronic liver disease patients in Kano, Nigeria. World J Transl Med 2026; 12(3): 124154
URL: https://www.wjgnet.com/2220-6132/full/v12/i3/124154.htm
DOI: https://dx.doi.org/10.5528/wjtm.124154

Manzo MGA, Audu N, Musa Y, Muktar AA, Samaila AA, Borodo MM. Serum zinc levels, hepatic encephalopathy, and liver disease severity in decompensated chronic liver disease patients in Kano, Nigeria. World J Transl Med 2026; 12(3): 124154 [DOI: 10.5528/wjtm.124154]

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