Risk factors for pathological upgrading pre- and post-endoscopic resection of colorectal adenoma: A retrospective study

doi:10.5528/wjtm.123433

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World Journal of Translational Medicine

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2220-6132

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Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Transl Med. Jul 28, 2026; 12(2): 123433
Published online Jul 28, 2026. doi: 10.5528/wjtm.123433

Table 2 Baseline characteristics of colorectal adenomas stratified into non-upgrading and pathological upgrading groups

Variables	Non-upgrading group (n = 151)	Pathological upgrading group (n = 49)	t/χ²	P value
Age (years)	58.83 ± 9.39	61.20 ± 11.70	1.289	0.202
BMI (kg/m²)	24.33 ± 3.28	23.76 ± 3.39	-1.063	0.289
Hb (g/L)	138.13 ± 14.59	131.25 ± 21.67	-2.075	0.042
PLT count (× 10⁹/L)	198.15 ± 62.15	201.88 ± 81.11	0.337	0.736
CEA (ng/mL)	1.89 ± 1.05	2.34 ± 1.89	1.594	0.116
Cholesterol (mmol/L)	5.11 ± 1.15	4.77 ± 1.32	-1.752	0.081
Triglycerides (mmol/L)	1.97 ± 1.53	1.71 ± 1.10	-1.11	0.268
Glucose (mmol/L)	5.91 ± 2.52	5.97 ± 2.04	0.149	0.882
Gender			0.044	0.834
Male	93 (61.6)	31 (63.3)
Female	58 (38.4)	18 (36.7)
Smoking			0.77	0.781
Yes	40 (26.4)	12 (24.5)
No	111 (73.6)	37 (75.5)
Drinking			0.081	0.775
Yes	34 (22.5)	12 (24.5)
No	117 (77.5)	37 (75.5)
Diabetes			0.042	0.838
Yes	17 (11.3)	5 (10.2)
No	134 (88.7)	44 (89.8)
Tumor history			2.793	0.095
Yes	10 (6.6)	7 (14.3)
No	141 (93.4)	42 (85.7)
Adenoma location			0.937	0.333
A group	61 (40.4)	16 (32.7)
B group	90 (59.6)	33 (67.3)
Adenoma diameter (mm)			51.144	0.000
≤ 20	148 (98.0)	30 (61.2)
> 20	3 (2.0)	19 (38.8)
Yamada classification			8.153	0.043
I	30 (19.9)	4 (8.2)
II	72 (47.7)	22 (44.9)
III	29 (19.2)	18 (36.7)
IV	20 (13.2)	5 (10.2)
Mucosal surface hyperemia			10.269	0.001
No	86 (57.0)	15 (30.6)
Yes	65 (43.0)	34 (69.4)

BMI: Body mass index; Hb: Hemoglobin; PLT: Platelet; CEA: Carcinoembryonic antigen.

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Citation: Zheng XL, Chen T, Yu Y, Wang N, Jiang B, Yao Y, Zhao YF, Yu XX, Su CL. Risk factors for pathological upgrading pre- and post-endoscopic resection of colorectal adenoma: A retrospective study. World J Transl Med 2026; 12(2): 123433
URL: https://www.wjgnet.com/2220-6132/full/v12/i2/123433.htm
DOI: https://dx.doi.org/10.5528/wjtm.123433

Zheng XL, Chen T, Yu Y, Wang N, Jiang B, Yao Y, Zhao YF, Yu XX, Su CL. Risk factors for pathological upgrading pre- and post-endoscopic resection of colorectal adenoma: A retrospective study. World J Transl Med 2026; 12(2): 123433 [DOI: 10.5528/wjtm.123433]

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