©The Author(s) 2026.
World J Transl Med. Feb 12, 2026; 12(1): 113050
Published online Feb 12, 2026. doi: 10.5528/wjtm.v12.i1.113050
Published online Feb 12, 2026. doi: 10.5528/wjtm.v12.i1.113050
Table 1 Tumor organoid applications in drug screening
| Cancer type | Drug tested | Organoid response | Clinical relevance |
| Colorectal | 5-fluorouracil | Organoids responded well, mimicking patient responses | High |
| Ovarian | Platinum-based chemo | Identified platinum-resistant populations | High |
| Lung | EGFR inhibitors | EGFR-mutant organoids sensitive to inhibitors | Moderate |
- Citation: Agrawal H, Tanwar H, Gupta N. Tumor organoids in translational cancer research: Models for personalized therapy. World J Transl Med 2026; 12(1): 113050
- URL: https://www.wjgnet.com/2220-6132/full/v12/i1/113050.htm
- DOI: https://dx.doi.org/10.5528/wjtm.v12.i1.113050