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Systematic Reviews
©The Author(s) 2026.
World J Transl Med. Feb 12, 2026; 12(1): 113050
Published online Feb 12, 2026. doi: 10.5528/wjtm.v12.i1.113050
Table 1 Tumor organoid applications in drug screening
Cancer type
Drug tested
Organoid response
Clinical relevance
Colorectal5-fluorouracilOrganoids responded well, mimicking patient responsesHigh
OvarianPlatinum-based chemoIdentified platinum-resistant populationsHigh
LungEGFR inhibitorsEGFR-mutant organoids sensitive to inhibitorsModerate


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