Management of patients with a failed kidney transplant: Dialysis reinitiation, immunosuppression weaning, and transplantectomy

Figure 1 Suggested algorithm for the management of immunosuppression after allograft failure. ¹Continue antimetabolite and low-dose prednisone (usually 5 mg daily), calcineurin inhibitor dose reduction (or mTOR inh dose reduction if used as based-therapy); ²No live donor or not a re-allograft candidate; ³See text; ⁴Usually prednisone 5 mg daily ± low-dose calcineurin inhibitor (or low-dose mTOR inh if used as based-therapy). IS: Immunosuppression; mTOR inh: Mammalian target of rapamycin inhibitor; ± with or without.