Sucroferric oxyhydroxide monotherapy for hyperphosphatemia in Indian chronic kidney disease patients undergoing hemodialysis: A phase IV, single-arm, open-label study

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Jun 25, 2025 (publication date) through Apr 30, 2025

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World Journal of Nephrology

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2220-6124

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Nephrol. Jun 25, 2025; 14(2): 100117
Published online Jun 25, 2025. doi: 10.5527/wjn.v14.i2.100117

Table 5 Laboratory parameters at baseline and end of study (Day 84) (n = 94), n (%)

Parameter	Baseline (mean ± SD)	Day 84 (mean ± SD)	Change from baseline (mean ± SD)	P value (vs baseline)
Serum calcium (mg/dL)	8.87 ± 0.67	8.75 ± 0.90	0.12 ± 0.92	P > 0.05
Serum intact parathyroid hormone (pg/mL)	264.06 ± 196.70	236.89 ± 217.63	27.17 ± 150.89	P > 0.05
Hemoglobin (g/dL)	11.16 ± 2.11	11.36 ± 2.15	-0.21 ± 2.01	P > 0.05
Total red blood cell (million/cu.mm)	3.91 ± 0.92	4.19 ± 0.95	-0.28 ± 0.72	P > 0.05
Total white blood cell (cells/cu.mm)	7057.34 ± 2027.30	7341.11 ± 2010.73	-283.77 ± 2329.78	P > 0.05
Neutrophils	60.03 (10.42)	59.54 (11.38)	0.49 (12.69)	P > 0.05
Lymphocytes	29.35 (10.37)	29.57 (11.31)	-0.21 (10.81)	P > 0.05
Eosinophils	4.92 (3.75)	5.02 (4.14)	-0.10 (5.24)	P > 0.05
Monocytes	4.93 (2.40)	4.77 (3.06)	0.16 (2.92)	P > 0.05
Basophils	0.77 (0.35)	0.79 (0.43)	-0.01 (0.48)	P > 0.05
Platelet (thou/mm³)	2.38 ± 0.77	2.41 ± 0.84	-0.03 ± 0.81	P > 0.05
Hematocrit	34.44 (9.18)	37.58 (22.40)	3.14 (23.27)	P > 0.05
Serum glutamic-oxaloacetic transaminase (U/L)	23.97 ± 15.52	28.29 ± 18.32	-3.85 ± 20.79	P > 0.05
Serum glutamic pyruvic transaminase (U/L)	21.22 ± 14.84	28.21 ± 24.59	-6.98 ± 25.58	P < 0.05
Glucose (mg/dL)	138.38 ± 72.24	124.70 ± 53.52	13.68 ± 63.44	P > 0.05

Citation: Niranjan MR, Srinivasa S, Gupta V, Bhalla AK, Gaikwad A, Wangikar P, Suryawanshi S, Gajbe P. Sucroferric oxyhydroxide monotherapy for hyperphosphatemia in Indian chronic kidney disease patients undergoing hemodialysis: A phase IV, single-arm, open-label study. World J Nephrol 2025; 14(2): 100117
URL: https://www.wjgnet.com/2220-6124/full/v14/i2/100117.htm
DOI: https://dx.doi.org/10.5527/wjn.v14.i2.100117