Neurological manifestations of Zika virus infection

Table 2 Zika virus disease interim case definitions according to World Health Organization

Suspected case	Probable case	Confirmed case
A person presenting with rash and/or fever and at least one of the following signs or symptoms: Arthralgia, or Arthritis, or Conjunctivitis (non-purulent/ hyperaemic)	A suspected case with presence of: IgM antibody against Zika virus (with no evidence of infection with other flaviviruses) and An epidemiological link (contact with a confirmed case, or a history of residing in or travelling to an area with local transmission of Zika virus within 2 wk prior to onset of symptoms)	A person with laboratory confirmation of recent Zika virus infection: Presence of Zika virus RNA or antigen in serum or other samples, or IgM antibody against Zika virus positive and PRNT90 for Zika virus with titre ≥ 20 and Zika virus PRNT90 titre ratio ≥ 4 compared to other tested flaviviruses, and Exclusion of other flaviviruses

Available from: URL: http://www.who.int/csr/disease/zika/case-definition/en.