Brugnaro P, Morelli E, Cattelan F, Petrucci A, Panese S, Eseme F, Cavinato F, Barelli A, Raise E. Non-acquired immunodeficiency syndrome definings malignancies among human immunodeficiency virus-positive subjects: Epidemiology and outcome after two decades of HAART era. World J Virology 2015; 4(3): 209-218 [PMID: 26279983 DOI: 10.5501/wjv.v4.i3.209]
Corresponding Author of This Article
Dr. Pierluigi Brugnaro, Infectious Diseases Department, Civil Hospital “SS.Giovanni e Paolo”, Castello, 6776-30122 Venice, Italy. brugnarop@yahoo.com
Research Domain of This Article
Virology
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Virology. Aug 12, 2015; 4(3): 209-218 Published online Aug 12, 2015. doi: 10.5501/wjv.v4.i3.209
Non-acquired immunodeficiency syndrome definings malignancies among human immunodeficiency virus-positive subjects: Epidemiology and outcome after two decades of HAART era
Pierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise
Pierluigi Brugnaro, Erika Morelli, Francesca Cattelan, Andrea Petrucci, Sandro Panese, Franklyn Eseme, Francesca Cavinato, Andrea Barelli, Enzo Raise, Infectious Diseases Department, Civil Hospital “SS.Giovanni e Paolo”, 6776-30122 Venice, Italy
Author contributions: Brugnaro P and Raise E designed the format of the manuscript; Brugnaro P, Morelli E, Cattelan F, Petrucci A, Panese S, Eseme F, Cavinato F and Barelli A contributed equally to write the paper; and Brugnaro p revised the manuscript before submission.
Conflict-of-interest statement: The authors state that there is not conflict of interest to declare.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Pierluigi Brugnaro, Infectious Diseases Department, Civil Hospital “SS.Giovanni e Paolo”, Castello, 6776-30122 Venice, Italy. brugnarop@yahoo.com
Telephone: +39-41-5294886 Fax: +39-41-5294884
Received: November 27, 2014 Peer-review started: November 28, 2014 First decision: January 20, 2015 Revised: March 2, 2015 Accepted: May 27, 2015 Article in press: May 28, 2015 Published online: August 12, 2015
Core Tip
Core tip: Since the introduction of highly active antiretroviral therapy (HAART) the incidence of acquired immunodeficiency syndrome (AIDS)-defining diseases has declined. This has resulted in a significant improvement in survival of human immunodeficiency virus (HIV)-infected patients. However the incidence of non-AIDS defining cancers (NADCs) did not decrease, and this determines now a relevant burden of mortality among HIV-positive patients. The availability of an even more effective HAART along with chemotherapy and radiotherapy regimens suitable also for HIV-patients could improve the outcome of these patients in the setting of NADCs. Screening interventions to detect precancerous lesions are also of paramount importance in order to decrease mortality of NADCs.
