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World J Virol. Mar 25, 2021; 10(2): 62-68
Published online Mar 25, 2021. doi: 10.5501/wjv.v10.i2.62
Trends in the management of infectious disease under SARS-CoV-2 era: From pathophysiological comparison of COVID-19 and influenza
Masafumi Seki
Masafumi Seki, Division of Infectious Diseases and Infection Control, Tohoku Medical and Pharmaceutical University, Miyagi 983-8536, Japan
Author contributions: Seki M contributed to the data collection, patient care, handling of ethics issues, data analysis, writing of the manuscript, and funding.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Masafumi Seki, MD, Professor, Division of Infectious Diseases and Infection Control, Tohoku Medical and Pharmaceutical University, Fukumuro 1-12-1, Miyagino-ku, Miyagi 983-8536, Japan. m-seki@tohoku-mpu.ac.jp
Received: December 18, 2020
Peer-review started: December 18, 2020
First decision: January 7, 2021
Revised: January 16, 2021
Accepted: February 19, 2021
Article in press: February 19, 2021
Published online: March 25, 2021
Core Tip

Core Tip: We are focusing the differences and similarity of coronavirus disease 2019 (COVID-19) and Influenza, and review the characteristic pathophysiology and basic concepts of treatment and prevention for COVID-19. Primary influenza pneumonia is known to exist in addition to secondary bacterial pneumonia, however, pulmonary edema (alveolar flood) from a similar cytokine storm, as well as severe angiopathy should be considered in COVID-19.