Graft vs host disease impacts overall survival post allogeneic hematopoietic stem cell transplantation for acute lymphoblastic leukemia/lymphoma

Table 1 Baseline characteristics of the cohort n (%)

Characteristic	Entire cohort (n = 69)
Patient age in years, median (range)	21 (14-61)
Recipient gender, male	41 (59%)
Cell subtype
B-cell	50 (72)
T-cell	19 (28)
Philadelphia chromosome (B-cell)	16/50 (32)
Disease subtype
Lymphoblastic leukemia	52 (75)
Lymphoblastic lymphoma	17 (25)
Cytogenetic status
Standard	30 (43)
High risk	35 (51)
Missing	4 (6)
ECOG, median (range)	0 (0-2)
HCT-CI, median (range)	0 (0-5)
Gender mismatch	28 (41)
Female donor/male recipient	11 (16)
Donor type
MSD	58 (84)
MORD	2 (3)
MUD	3 (4)
Haploidentical	6 (9)
Status at HCT
CR1	42 (61)
≥ CR2	27 (39)
ABO matching
Match	50 (73)
Major/bidirectional	10 (14)
Minor	9 (13)
TBI containing regimen	60 (87)
Conditioning intensity
MAC	62 (90)
RIC/NMA	7 (10)

ECOG: Eastern Cooperative Oncology Group; HCT-CI: Hematopoietic stem cell transplant comorbidity index; MSD: Matched sibling donor; MORD: Matched other related donor; MUD: Matched unrelated donor; CR: Complete remission; TBI: Total body irradiation; MAC: Myeloablative conditioning; RIC/NMA: Reduced intensity conditioning/non-myeloablative.