Copyright
©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Transplant. Mar 24, 2016; 6(1): 155-164
Published online Mar 24, 2016. doi: 10.5500/wjt.v6.i1.155
Published online Mar 24, 2016. doi: 10.5500/wjt.v6.i1.155
Donor to recipient sizing in thoracic organ transplantation
Michael Eberlein, Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, United States
Robert M Reed, Division of Pulmonary and Critical Care Medicine, University of Maryland, Baltimore, MD 21201, United States
Author contributions: Eberlein M and Reed RM contributed to this paper in conception and design, acquisition, analysis and interpretation of data, and drafting the article and revising it critically for important intellectual content; all authors approved this version to be published.
Supported by Flight Attendants Medical Research Institute in part (to Robert M Reed); Michael Eberlein is supported by a PILOT grant from the Institute for Clinical and Translational Science (ICTS) at the University of Iowa via the National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program, grant 2 UL1 TR000442-06.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributed their efforts in this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Michael Eberlein, MD, PhD, Division of Pulmonary, Critical Care and Occupational Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, C 33 GH, Iowa City, IA 52242, United States. michael-eberlein@uiowa.edu
Telephone: +1-319-3561265 Fax: +1-319-3536406
Received: July 29, 2015
Peer-review started: August 19, 2015
First decision: September 22, 2015
Revised: November 17, 2015
Accepted: December 7, 2015
Article in press: December 8, 2015
Published online: March 24, 2016
Peer-review started: August 19, 2015
First decision: September 22, 2015
Revised: November 17, 2015
Accepted: December 7, 2015
Article in press: December 8, 2015
Published online: March 24, 2016
Core Tip
Core tip: Recipients for lung transplant and heart transplant are listed with acceptable donor height and weight ranges as surrogates for organ size, respectively. While these measures are important predictors of organ size, they are crude surrogates that fail to incorporate the influence of sex on organ size. Lung size can be better estimated using the predicted total lung capacity (derived from height, sex and age). Similarly, heart size can be better estimated using the predicted heart mass (derived from sex, age, height, and weight). These refined organ sizing-measures perform better than current sizing practice for the prediction of outcomes after transplantation.