White matter alterations in anorexia nervosa: A systematic review of diffusion tensor imaging studies

Table 2 Characteristics of the participant samples in the reported studies

Ref.	AN subtype	Total size	Sample characteristics
			n
			Gender
			Mean ± SD:
			Age/years
			BMI
			Duration of illness/years
			ED group (AN)	Recovered AN	Healthy group
Kazlouski et al[13]	Current AN restricting and purging subtype	n = 33	n = 16 (10 resAN, 6 purgAN)	-	n = 17
			Female		Female
			23.9 ± 7 SD		25.1 ±4 SD
			16.5 ± 1 SD		21.5 ±1 SD
			7.5 ± 8 SD		NA
Frank et al[49]	Current AN restricting and purging subtype	n = 41	n = 19 (17 resAN, 2 purgAN)	-	n =22
			NS		Female
			15.4 ± 1.4 SD		14.8 ± 1.8 SD
			16.2 ± 1.1 SD		21.3 ± 1.9 SD
			NS		NA
Nagahara et al[7]	Current AN, NS subtype	n = 35	n = 17	-	n = 18
			Female		Female
			23.8 ± 6.68 SD		26.2 ± 5.6 SD
			13.6 ± 1.3 SD		19.9 ± 2.0 SD
			4.93 ± 4.9 SD		NA
Via et al[53]	Current AN restricting subtype	n = 38	n = 19	-	n = 19
			Female		Female
			28.37 ± 9.55 SD		28.63 ± 8.58 SD
			17.03 ± 1.09 SD		21.09 ± 1.80 SD
			6.52 ± 6.03 SD		NA
Frieling et al[5]	Current AN with NS subtype and recovered women from AN	n = 41	n = 12	n = 9	n = 20
			Female	Female	Female
			26.8 ± 6.94 SD	27.44 ± 5.3 SD	24.80 ± 2.6 SD
			15.18 ± 1.39 SD	19.31 ± 1.39 SD	19.60 ± 0.94 SD
			NS	NS	NA
Yau et al[39]	Recovered women from restricting type AN	n = 22	-	n = 12	n = 10
				Female	Female
				28.7 ± 7.9 SD	26.7 ± 5.4 SD
				21.2 ± 1.5 SD	22.0 ± 1.1. SD
				5.6 ± 5.2	NA

AN: Anorexia nervosa; recAN: Recovered anorexia nervosa; purgAN: Purgative subtype anorexia nervosa; resAN: Restrictive subtype anorexia nervosa; BMI: Body mass index; NA: Non-applicable; NS: Non-specified.