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©The Author(s) 2025.
World J Psychiatry. Aug 19, 2025; 15(8): 107791
Published online Aug 19, 2025. doi: 10.5498/wjp.v15.i8.107791
Table 4 Summary of studies on prepulse inhibition and prepulse facilitation in the cohorts of participants with obsessive-compulsive disorder, mean ± SD
Ref.
Groups (group size)
Mean age
Side of recording
Lead interval, ms
PPI
PPF
Hoenig et al[93]OCD (34)/Contr (33)31.5 ± 1.6Right120OCD < ContrNA
Swerdlow et al[94]OCD (34)/Contr (33)36.2 ± 2.1Right100OCD < ContrNA
de Leeuw et al[95]Unmedicated OCD (25)/Contr (25)32 ± 7.4Right100No differenceNA
Ahmari et al[96]Unmedicated OCD (22)/Contr (22)31 ± 6.3Right100OCD < ContrNA
Schleyken et al[97]Treatment refractory OCD (15)/Contr (21)20-64 (range)Right60, 120, 200No differenceNA
Steinman et al[98]Unmedicated OCD (45)/Contr (62)28.2 ± 4.3Right120OCD < Contr (in female only)NA


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