Catatonia and autism spectrum disorder: A common comorbid syndrome or a core feature?

Table 6 Applying Robins and Guze validity criteria to autism spectrum disorder in relation to catatonia[90]

Robins and Guze factors[90]	Criteria satisfaction
Clinical description	Several identical features between catatonia and ASD
Exclusion of other disorders	It is challenging to exclude and differentiate both syndromes from each other based on criteria
Follow up studies	Good response to similar modalities of treatment, such as lorazepam and ECT; ASD-related catatonia may be more chronic than catatonia associated with mood, psychotic, and systemic medical disorders
Laboratory studies	This area is in its infancy. However, a significant report shows an overlap in neurobiology
Family studies	No data available

ASD: Autism spectrum disorder; ECT: Electroconvulsive therapy.