Management of acute carbamazepine poisoning: A narrative review

Table 1 Clinical outcomes of the 67 patients described in the case reports

Patient demographics	Values
Median age (yr)	25 (1.5-85)
Male sex	49.3
Poisoning exposure
Mean peak carbamazepine concentration in mg/L	39.0 (17.7-93.8)
Clinical symptoms and signs
Respiratory depression	47.8
Decreased consciousness	100
Seizure	20.9
Hypotension	14.9
Dysrhythmias	19.4
Treatment measure1
Supportive care	9.0
Gastric lavage	29.9
Multiple-dose activated charcoal	58.2
Hemoperfusion	22.4
Hemodialysis	22.4
Continuous renal replacement treatment	12.0
Plasma exchange and plasmapheresis	4.5
Lipid resuscitation therapy	4.5
Outcome
Recovery	82.0
Sequelae	12.0
Fatalities	6.0

¹Some patients received more than one treatment.

Data are presented as n (range) or %. The source of cases is listed in Supplement Material.