Identification of key genes involved in post-traumatic stress disorder: Evidence from bioinformatics analysis

Table 2 Kyoto Encyclopedia of Genes and Genomes analysis of differentially expressed genes associated with post-traumatic stress disorder (top 10)

Expression	Term	Definition	Count	P value
Upregulated	mmu04080	Neuroactive ligand-receptor interaction	16	2.02E–05
	mmu05014	ALS	6	1.08E–04
	mmu04530	Tight junction	8	1.23E–03
	mmu00430	Taurine and hypotaurine metabolism	2	1.30E–03
	mmu04020	Calcium signaling pathway	9	2.08E–03
	mmu00650	Butanoate metabolism	3	3.77E–03
	mmu04512	ECM-receptor interaction	5	6.91E–03
	mmu05322	Systemic lupus erythematosus	7	8.98E–03
	mmu04720	Long-term potentiation	4	1.25E–02
	mmu04010	MAPK signaling pathway	10	1.31E–02
Downregulated	mmu05223	Non-small cell lung cancer	9	1.48E–05
	mmu05212	Pancreatic cancer	10	2.35E–05
	mmu05160	Hepatitis C	14	4.31E–05
	mmu05211	Renal cell carcinoma	8	6.64E–04
	mmu05221	Acute myeloid leukemia	7	6.55E–04
	mmu04012	ErbB signaling pathway	9	6.19E–04
	mmu04620	Toll-like receptor signaling pathway	10	5.05E–04
	mmu03013	RNA transport	14	3.89E–04
	mmu05214	Glioma	8	3.55E–04
	mmu05215	Prostate cancer	10	1.91E–04

ALS: Amyotrophic lateral sclerosis; ECM: Extracellular matrix.