Validity, reliability, and psychometric properties of a computerized, cognitive assessment test (Cognivue®)

Table 2 Summary of the purpose and analyses of the components of the Food and Drug Administration pivotal clinical trial of Cognivue^®

Validation of classification scores	Purpose: Assess the validity of the previously defined Cognivue® cut-off scores in a larger sample of subjects
	Methods: Scores on Cognivue® and SLUMS were compared using regression and classification analyses. PPA and NPA were calculated
Assessment of retest reliability	Purpose: Compare scores from repeated administration of Cognivue® to assess retest reliability, compare findings to parallel results from SLUMS
	Methods: Repeated Cognivue® and SLUMS testing was conducted in 2 sessions 1-2 wk apart with regression and rank linear regression analysis being performed
Assessment of score psychometrics vs other neuropsychological tests	Purpose: Compare scores on Cognivue® and other neuropsychological tests to describe relationship and compare them to SLUMS
	Methods: 401 participants completed 10 different tests [SLUMS, SLUMS-clock drawing1, SLUMS-animal naming1, RAVLT, TMT-A, TMT-B, Benton JOLO, figural memory, PPB, HVCS, GDS (15-item)]; rank linear regression analysis and factor analysis performed

¹Scored separately from overall St. Louis University Mental Status. GDS: Geriatric Depression Scale; HVCS: Hamilton-Veale Contrast Sensitivity; JOLO: Judgment of line orientation; NPA: Negative percent agreement; PPA: Positive percent agreement; PPB: Purdue Peg Board; RAVLT: Rey Auditory Verbal Learning Test; SLUMS: St. Louis University Mental Status; TMT-A: Trail Making Test-A; TMT-B: Trail Making Test-B.