Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?

Table 3 Estimated numbers of adult patients treatable from plant-based artemisinin combination therapy¹

For A. annua cultivar containing	Number of patients treated at various dry leaf tonnage
	2 T/ha2	3 T/ha	4 T/ha3	5 T/ha
0.7% artemisinin/g DW (Kenyan cultivar)	127260	190890	254520	318150
1.4% artemisinin/g DW (WPI cultivar)	254520	381780	509040	636300

¹Assumptions: each adult needs 100 mg artemisinin (AN) over 6 d for a cure; at 0.7% and 1.4% AN that is approximately 15 and 7.5 g DW leaves, respectively, for a single adult total malaria treatment;

²Below the average of 2.5 T/ha reported for all of East Africa;

³Equal to the maximum obtained growing A. annua SAM in the Stow, MA, United States field trials. A. annua: Artemisia annua.