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©2014 Baishideng Publishing Group Inc.
World J Pharmacol. Dec 9, 2014; 3(4): 39-55
Published online Dec 9, 2014. doi: 10.5497/wjp.v3.i4.39
Published online Dec 9, 2014. doi: 10.5497/wjp.v3.i4.39
Table 2 Kenyan human trial data[20] for orally delivered dried leaf Artemisia annua (plant-based artemisinin combination therapy)
| pACT (dried leaf A. annua tablets, ea 500 mg, 3.7 mg artemisinin/tablet) | |||||
| Artemisinin dose (mg) | No. ofpatients | Leaf DW (g) | %Recrudescence | ||
| Day 1 | Days 2-6 | Day 1 | Days 2-6 | ||
| 7.4 × 2 | 3.7 × 2 | 12 | 2 | 1 | 25 |
| 11.1 × 2 | 7.4 × 2 | 12 | 3 | 2 | 9.1 |
| 14.8 × 2 | 11.1 × 2 | 12 | 4 | 3 | 16.7 |
| 18.5 × 2 | 14.8 × 2 | 12 | 5 | 4 | 9.1 |
| Compare to orally delivered pure artemisinin[39] | |||||
| Day 1 | Day 2-7 | ||||
| 500 × 2 | 500 | 227 | NA | 24 | |
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Citation: Weathers PJ, Towler M, Hassanali A, Lutgen P, Engeu PO. Dried-leaf
Artemisia annua : A practical malaria therapeutic for developing countries? World J Pharmacol 2014; 3(4): 39-55 - URL: https://www.wjgnet.com/2220-3192/full/v3/i4/39.htm
- DOI: https://dx.doi.org/10.5497/wjp.v3.i4.39