Use of eltrombopag in thrombocytopenia of liver disease

doi:10.5497/wjp.v3.i4.186

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World Journal of Pharmacology

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2220-3192

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Pharmacol. Dec 9, 2014; 3(4): 186-192
Published online Dec 9, 2014. doi: 10.5497/wjp.v3.i4.186

Table 1 Mechanisms of thrombocytopenia in liver disease

In chronic liver disease

Decreased Thrombopoietin production

Splenic sequestration

Autoantibodies against platelets

Expansion of plasma volume

Bone marrow suppression (Alcohol)

In specific liver diseases

Viral or alcohol related marrow suppression

Autoimmune thrombocytopenia

Cryoglobulins

Drugs: Interferon mediated marrow suppression

Citation: Sharma V. Use of eltrombopag in thrombocytopenia of liver disease. World J Pharmacol 2014; 3(4): 186-192
URL: https://www.wjgnet.com/2220-3192/full/v3/i4/186.htm
DOI: https://dx.doi.org/10.5497/wjp.v3.i4.186