Mazdutide: An emerging glucagon/GCG-like peptide-1 dual receptor agonist for obesity—a comparison of therapeutic effects and potential side effects with GCG-like peptide-1 inhibitors

doi:10.5497/wjp.v15.i1.113080

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World Journal of Pharmacology

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2220-3192

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Pharmacol. Jan 19, 2026; 15(1): 113080
Published online Jan 19, 2026. doi: 10.5497/wjp.v15.i1.113080

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Figure 2 Physiological effects of glucagon-like peptide-1. The physiological effects of glucagon-like peptide-1 (GLP-1) are extensive. GLP-1: Glucagon-like peptide-1; POMC: Pro-opiomelanocortin; CART: Cocaine amphetamine regulated transcript; NPY: Neuropeptide Y; AgRP: Agouti-related peptide.

Citation: Deng CX, Chen ZM, Tang YX, Xi ZX, Wang SY, Wu HY, Xu B, Xu TC. Mazdutide: An emerging glucagon/GCG-like peptide-1 dual receptor agonist for obesity—a comparison of therapeutic effects and potential side effects with GCG-like peptide-1 inhibitors. World J Pharmacol 2026; 15(1): 113080
URL: https://www.wjgnet.com/2220-3192/full/v15/i1/113080.htm
DOI: https://dx.doi.org/10.5497/wjp.v15.i1.113080

Deng CX, Chen ZM, Tang YX, Xi ZX, Wang SY, Wu HY, Xu B, Xu TC. Mazdutide: An emerging glucagon/GCG-like peptide-1 dual receptor agonist for obesity—a comparison of therapeutic effects and potential side effects with GCG-like peptide-1 inhibitors. World J Pharmacol 2026; 15(1): 113080 [DOI: 10.5497/wjp.v15.i1.113080]

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