Antidepressant-like potential of silymarin and silymarin-sertraline combination in mice: Highlighting effects on behaviour, oxidative stress, and neuroinflammation

Figure 6 Effect of silymarin on time spent in the open-arm (upper panel) and closed arm (lower panel) of the elevated plus maze. Each bar represents the mean ± SEM, ^aP < 0.05 vs control, ^bP < 0.05 vs SERT, ^cP < 0.05 vs DEX, ^dP < 0.05 vs DEX/SERT. SERT: Sertraline; DEX: Dexamethasone; SILY: Silymarin. Number of mice per treatment group = 10.