An inhibitor of HIF-α subunit expression suppresses hypoxia-induced dedifferentiation of human NSCLC into cancer stem cell-like cells

Figure 2 Expression of hypoxia-inducible factor α subunits and cell growth in A549 and QG56 cells under hypoxic conditions. The cells were cultured under normoxic (N) or hypoxic (H) conditions. A: Expression of hypoxia-inducible factor (HIF)-1α and HIF-2α mRNA; B: Cell growth of A549; C: Cell growth of QG56 cells; D: Cell viability; The cells were cultured for 5 d; Bars, SD (n = 3).