Systems biology applications to study mechanisms of human immunodeficiency virus latency and reactivation

Figure 3 Transcriptional and post-transcriptional mechanisms of regulation of human immunodeficiency virus expression. Pathway and GO term categories related to transcriptional and post-transcriptional regulation of HIV expression, identified in gene expression studies that compared latently infected and uninfected cells, are shown. Dark blue, Iglesias-Ussel et al[19]; Red, Mohammadi et al[42]; Brown, Evans et al[76]; Yellow, Krishnan and Zeichner[18]. GO: Gene ontology; HIV: Human immunodeficiency virus; mTOR: Mammalian target of rapamycin.