Localization of ATP-sensitive K+ channel subunits in rat liver

Figure 12 Immunofluorescence double staining for ATP-sensitive K⁺ channel subunits Kir6. 1, Kir6.2, SUR1, SUR2A and SUR2B with SE-1. Immunofluorescence double staining for ATP-sensitive K⁺ channel subunits Kir6.1, Kir6.2, SUR1, SUR2A and SUR2B (A, D, G, J, and M) with SE-1 [marker of sinusoidal endothelial cells (SECs)]; In the liver sections, SECs showed immunopositive reactivity to SE-1 (B, E, H, K, and N); A few SE-1⁺ cells colocalized with Kir6.1 (C, arrows), but a number of them colocalized with Kir6.2 (F, arrows); As for SURs, some SE-1⁺ cells colocalized with SUR1 (I, arrows) and/or SUR2B (O, arrows); Most SE-1⁺ cells colocalized with SUR2A (L, arrows). Bars: 20 µm.