Lipofuscins prepared by modification of photoreceptor cells via glycation or lipid peroxidation show the similar phototoxicity

Table 1 Superoxide generation rate in model and natural lipofuscins

Sample name	Superoxide generation rate nmole/min mg wet weight
Model lipofuscin from oxidized POS (LPO-lipofuscin)	8.5 ± 0.6
Model lipofuscin obtained from not oxidized POS in the presence of fructose (LFF-lipofuscin)	9.2 ± 0.4
Natural lipofuscin from human eye	15.7 ± 0.8

Data represents mean values of 5 measurements on each type of lipofuscin with standard deviation, P < 0.05. POS: Photoreceptor outer segments.