Gas chromatography-mass spectrometry-based plasma metabolomics analysis in hypertensive patients with Yin deficiency and Yang hyperactivity syndrome

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Sep 20, 2025 (publication date) through Aug 16, 2025

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World Journal of Experimental Medicine

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2220-315x

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Exp Med. Sep 20, 2025; 15(3): 103154
Published online Sep 20, 2025. doi: 10.5493/wjem.v15.i3.103154

Table 3 Metabolic pathways of differential metabolites

Pathway	Hits/Total	Expected	Impact	P value
Linoleic acid metabolism	1/5	0.041935	1	0.041
Alanine, aspartate, and glutamate metabolism	4/28	0.23484	0.50722	< 0.01
D-Glutamine and D-glutamate metabolism	1/6	0.050323	0.5	0.049
Arginine biosynthesis	2/14	0.11742	0.11675	< 0.01

Citation: Jialiken D, Dai J, Fan YD, Zhang HT, Shan JJ, Xu WC, Zou C. Gas chromatography-mass spectrometry-based plasma metabolomics analysis in hypertensive patients with Yin deficiency and Yang hyperactivity syndrome. World J Exp Med 2025; 15(3): 103154
URL: https://www.wjgnet.com/2220-315X/full/v15/i3/103154.htm
DOI: https://dx.doi.org/10.5493/wjem.v15.i3.103154