Gas chromatography-mass spectrometry-based plasma metabolomics analysis in hypertensive patients with Yin deficiency and Yang hyperactivity syndrome

Table 1 Baseline comparison

Project	Healthy subjects	Hypertension (YDYHS)	Normal reference	t/Z	P value
WBC (× 109/L)	5.4860 ± 1.04219	6.7019 ± 1.52323	4.00-10.00	3.254	0.002a
RBC (× 1012/L)	4.7685 ± 0.41509	4.8728 ± 0.50817	4.00-5.50	0.809	0.422
Hb (g/L)	141.85 ± 14.147	145.79 ± 13.779	120-160	1.062	0.292
PLT (× 109/L)	236.45 ± 51.953	235.53 ± 47.571	100-300	-0.070	0.944
ALT (U/L)	14 (12, 17)	22 (15, 27)	< 42	-3.677	0.000a
AST (U/L)	17 (15, 19)	18 (16, 24)	< 38	-2.315	0.021a
TBil (μmol/L)	11.41 (8.84, 16.28)	11.10 (9.19, 15.28)	5.10-28.00	-0.319	0.750
ALP (U/L)	77.45 ± 18.349	83.12 ± 22.374	45-125	1.005	0.319
GGT (U/L)	14 (12, 19)	22 (16, 30)	11-50	-3.232	0.001a
CR (μmol/L)	72.4 (59.9, 84.4)	67.1 (59.8, 76.6)	44.0-110.0	-0.917	0.359
BUN (mmol/L)	4.12 (3.51, 4.87)	4.96 (4.13, 5.90)	2.86-8.20	-2.899	0.004a
Glu (mmol/L)	4.54 (4.31, 4.86)	5.54 (5.21, 5.95)	3.89-6.11	-5.474	0.000a

^aP < 0.05, there is statistical difference between the two groups. ALT: Alanine transaminase; AST: Aspartate transaminase; GGT: Gamma-glutamyl transferase; BUN: Blood urea nitrogen; Glu: Glucose; WBC: White blood cells; RBC: Red blood cells; Hb: Hemoglobin; PLT: Platelets; CR: Creatinine.