Association between thrombomodulin and high mobility group box 1 in sepsis patients

doi:10.5492/wjccm.v9.i4.63

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Crit Care Med. Oct 18, 2020; 9(4): 63-73
Published online Oct 18, 2020. doi: 10.5492/wjccm.v9.i4.63

Table 5 Association between levels of thrombomodulin, high mobility group box 1 and the thrombomodulin/high mobility group box 1 ratio and renal replacement therapy

	RRT (case group, n = 20)
	Yes (n = 10)	No (n = 10)	P value¹
HMGB1 (pg/mL)	236.00 ± 84.00	346.90 ± 130.10	0.026²
TM (pg/mL)	75.37 ± 27.49	34.60 ± 22.58	0.002³
T/H	0.38 ± 0.14	0.11 ± 0.09	< 0.001³

¹Represent t test.

²Power for comparing two means (PCTM) > 80%.

³PCTM < 80%. TM: Thrombomodulin; HMGB1: High mobility group box 1; T/H: Thrombomodulin ratio/high mobility group box 1; RRT: Renal replacement therapy.

Citation: Rodrigues AT, Rodrigues JT, Rodrigues CT, Volpe CMO, Rocha-Silva F, Nogueira-Machado JA, Alberti LR. Association between thrombomodulin and high mobility group box 1 in sepsis patients. World J Crit Care Med 2020; 9(4): 63-73
URL: https://www.wjgnet.com/2220-3141/full/v9/i4/63.htm
DOI: https://dx.doi.org/10.5492/wjccm.v9.i4.63