Association between thrombomodulin and high mobility group box 1 in sepsis patients

doi:10.5492/wjccm.v9.i4.63

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Oct 18, 2020 (publication date) through Apr 25, 2024

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World Journal of Critical Care Medicine

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2220-3141

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Crit Care Med. Oct 18, 2020; 9(4): 63-73
Published online Oct 18, 2020. doi: 10.5492/wjccm.v9.i4.63

Table 4 Levels of thrombomodulin, high mobility group box 1, thrombomodulin/high mobility group box 1 ratio and the presence of sepsis-induced coagulopathy

	Cases (n = 20)
	With SIC (n = 8)	Without SIC (n = 12)	P value¹
HMGB1 (pg/mL)	264.04 ± 84.01	309.22 ± 138.97	0.422
TM (pg/mL)	74.78 ± 28.95	38.44 ± 24.56	0.007²
T/H	0.32 ± 0.16	0.16 ± 0.13	0.034³

¹Represent t test.

²Power for comparing two means (PCTM) > 80%.

³PCTM < 80%. TM: Thrombomodulin; HMGB1: High mobility group box 1; T/H: Thrombomodulin/high mobility group box 1 ratio; SIC: Sepsis-induced coagulopathy.

Citation: Rodrigues AT, Rodrigues JT, Rodrigues CT, Volpe CMO, Rocha-Silva F, Nogueira-Machado JA, Alberti LR. Association between thrombomodulin and high mobility group box 1 in sepsis patients. World J Crit Care Med 2020; 9(4): 63-73
URL: https://www.wjgnet.com/2220-3141/full/v9/i4/63.htm
DOI: https://dx.doi.org/10.5492/wjccm.v9.i4.63