Clinical decision support for drug related events: Moving towards better prevention

Table 5 Summary of proposed approaches to developing clinical decision support to prevent adverse drug events

Proposed approach	Description
Trajectory analysis	Identify laboratory values as they are on the incline or decline before they reach a critical value
Biomarkers	Use biomarkers that identify patients at risk for organ damage
Drug combinations	Generate alerts for drug combinations that place the patient at risk for drug-induced injury
Drug induced physiologic events	Add alerts for possible drug induced alterations in physiologic parameters to clinical decision support
Predictive analytics and forecasting models	Develop models that predict possible drug induced injury based on risk factors and use this information for advanced alerts using machine learning for adaptive response