Impact of nurse empowerment for early adrenaline administration for in-hospital cardiac arrest resuscitation: A pre-post intervention study

doi:10.5492/wjccm.119122

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 15, Issue 3

This Article

(0)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Critical Care Medicine

ISSN

2220-3141

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Crit Care Med. Sep 9, 2026; 15(3): 119122
Published online Sep 9, 2026. doi: 10.5492/wjccm.119122

Table 3 Comparison of patients who received adrenaline within 2 minutes of arrest vs those who didn’t¹

Parameter	All patients (n = 426)²	Adrenaline ≤ 2 minutes (n = 274)	Adrenaline > 2 minutes (n = 152)	P value
Age, mean ± SD years	52.7 ± 16.0	51.7 ± 16.0	54.5 ± 16.0	0.08
Gender, male	270 (63.4)	172 (62.8)	98 (64.5)	0.75
Initial arrest rhythm
Asystole	402 (94.4)	261 (95.3)	141 (92.8)	0.28
PEA	24 (5.6)	13 (4.7)	11 (7.2)
Time to CART activation, median (IQR)	2 (1, 5)	1 (0, 3)	3 (1, 6)	< 0.001
Number of cycles of CPR, median (IQR)	10 (6, 16)	9 (5, 15)	10 (7, 16)	0.02
Number of adrenaline doses, median (IQR)	4 (2, 7)	4 (3, 7)	4 (2, 6)	0.08
Reversible cause identified	304 (71.4)	213 (77.7)	91 (60)	< 0.001
Outcomes among those who achieved ROSC
Number who achieved ROSC	242 (56.8)	166 (60.6)	76 (50)	0.04
Time to achieve ROSC, median (IQR)	16 (10, 28)	14 (8, 26)	20.5 (12, 30)	0.006
Survival at 24 hours following ROSC	130 (53.7)	87 (52.4)	43 (56.6)	0.58
Survival to hospital discharge among ROSC	47 (19.4)	29 (17.5)	18 (23.7)	0.29

¹Data was available only for 426 patients; all values are numbers (n) and percentages (%) unless specified.

²The time of administration of adrenaline was available only for 426 of the 450 patients.

IQR: Interquartile range; ROSC: Return of spontaneous circulation; CPR: Cardiopulmonary resuscitation; CART: Cardiac arrest resuscitation team; PEA: Pulseless electrical activity.

Full Size Table

Citation: Chacko B, Jacob AS, Thomas L, L A, John SAS, Sanghi AE, P NR, Rao SV, Adhikari DD, Vijayananthan S, Anita EA, V A, Yadav B, Peter JV. Impact of nurse empowerment for early adrenaline administration for in-hospital cardiac arrest resuscitation: A pre-post intervention study. World J Crit Care Med 2026; 15(3): 119122
URL: https://www.wjgnet.com/2220-3141/full/v15/i3/119122.htm
DOI: https://dx.doi.org/10.5492/wjccm.119122

Chacko B, Jacob AS, Thomas L, L A, John SAS, Sanghi AE, P NR, Rao SV, Adhikari DD, Vijayananthan S, Anita EA, V A, Yadav B, Peter JV. Impact of nurse empowerment for early adrenaline administration for in-hospital cardiac arrest resuscitation: A pre-post intervention study. World J Crit Care Med 2026; 15(3): 119122 [DOI: 10.5492/wjccm.119122]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.