Outcomes of acute kidney injury in critically ill adults with tropical acute febrile illness: Prospective observational study

Table 4 Exploratory multivariable logistic regression analyses for net negative outcome at hospital discharge

Variable	β (SE)	Odds ratio, exp (β)	95%CI for OR	P value
Age (years)	-0.086 (0.039)	0.917	0.849-0.990	0.027
Fever duration (days)	-0.177 (0.072)	0.838	0.728-0.965	0.014
FiO2 on admission	0.076 (0.026)	1.079	1.025-1.137	0.004
Serum creatinine on admission (mg/dL)	-0.051 (0.441)	0.951	0.401-2.256	0.909
Worst serum creatinine (mg/dL)	0.182 (0.533)	1.2	0.422-3.414	0.733
APACHE-II on admission	0.343 (0.140)	1.41	1.071-1.856	0.014
APACHE-II at 48 hours	-0.222 (0.142)	0.801	0.606-1.059	0.119
SOFA score on admission	-0.540 (0.244)	0.582	0.361-0.940	0.027
SOFA score at 48 hours	0.404 (0.252)	1.497	0.914-2.454	0.109
Dialysis requirement	-3.176 (0.996)	0.042	0.006-0.294	0.001

Model statistics: Omnibus χ² = 38.57, df = 10, P < 0.001; -2 Log likelihood = 48.45; Cox & Snell R² = 0.433; Nagelkerke R² = 0.600; Hosmer-Lemeshow χ² = 5.62, df = 8, P = 0.690. Disclaimer: Binary logistic regression models were used. Odds ratios (OR) < 1 indicate reduced odds of adverse outcome with increasing predictor values. Variables with P < 0.05 were considered statistically significant. Results should be interpreted cautiously given the limited number of outcome events. APACHE-II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential organ failure assessment; OR: Odds ratio; CI: Confidence interval.