Outcomes of acute kidney injury in critically ill adults with tropical acute febrile illness: Prospective observational study

Table 3 Exploratory multivariable logistic regression analyses for in-hospital mortality

Variable	β (SE)	Odds ratio, exp (β)	95%CI for OR	P value
Age (years)	-0.117 (0.054)	0.889	0.800-0.989	0.030
Fever duration (days)	-0.269 (0.144)	0.764	0.576-1.014	0.062
FiO2 on admission	0.091 (0.042)	1.095	1.008-1.190	0.032
Serum creatinine on admission (mg/dL)	0.982 (0.750)	2.671	0.614-11.619	0.190
Worst serum creatinine (mg/dL)	-0.307 (0.839)	0.736	0.142-3.808	0.714
APACHE-II on admission	0.422 (0.217)	1.525	0.997-2.333	0.052
APACHE-II at 48 hours	-0.395 (0.261)	0.673	0.403-1.124	0.130
SOFA score on admission	-0.877 (0.470)	0.416	0.165-1.046	0.062
SOFA score at 48 hours	0.684 (0.543)	1.981	0.684-5.743	0.208
Dialysis requirement	-0.867 (1.407)	0.42	0.027-6.618	0.538

Model statistics: Omnibus χ² = 21.83, df = 10, P = 0.016; -2 Log likelihood = 27.43; Cox & Snell R² = 0.275; Nagelkerke R² = 0.533; Hosmer-Lemeshow χ² = 1.59, df = 8, P = 0.991. Disclaimer: Binary logistic regression models were used. Odds ratios (OR) < 1 indicate reduced odds of adverse outcome with increasing predictor values. Variables with P < 0.05 were considered statistically significant. Results should be interpreted cautiously given the limited number of outcome events. APACHE-II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential organ failure assessment; OR: Odds ratio; CI: Confidence interval.