Outcomes of acute kidney injury in critically ill adults with tropical acute febrile illness: Prospective observational study

Table 2 Univariate analysis for in-hospital mortality

Variable	Survivors (n = 60)	Non-survivors (n = 8)	P value
Age (years)	54 (39-61)	45 (26-60)	0.319
Hospital stay (days)	9 (6-13)	6 (4-9)	0.192
FiO2 on admission (%)	32 (21-53)	55 (25-67)	0.099
Hemoglobin on admission (g/dL)	10.9 ± 1.8	9.6 ± 4.1	0.115
Serum creatinine on admission (mg/dL)	1.35 (0.9-2.9)	1.28 (0.6-5.7)	0.165
APACHE-II on admission	15.1 ± 7.4	19.1 ± 10.6	0.176
SOFA score on admission	8.7 ± 3.8	8.5 ± 4.3	0.919
Bleeding	5 (7.4)	3 (37.5)	0.016
NIV use during ICU stay	6 (10.0)	3 (37.5)	0.031
Blood product transfusion	6 (10.0)	4 (50.0)	0.003
Dengue infection	13 (21.7)	5 (62.5)	0.014
AKI stage ≥ 2 on admission	25 (41.7)	4 (50.0)	0.848
Dialysis requirement	16 (26.7)	3 (37.5)	0.521
Renal non-recovery at discharge	2 (3.3)	8 (100)	< 0.001
Invasive ventilation	24 (40.0)	3 (37.5)	0.892
Vasopressor use	26 (43.3)	2 (25.0)	0.322

Presented as mean ± SD, n (%) or median (IQR). Variables with P < 0.10 were considered for multivariable analysis. AKI: Acute kidney injury; APACHE-II: Acute Physiology and Chronic Health Evaluation II; ICU: Intensive care unit; IQR: Interquartile range; NIV: Non-invasive ventilation; SOFA: Sequential organ failure assessment.